Inhibition of bacteria and white-rot-fungi by newly synthesized furfural derivatives

VIEWS - 1091 (Abstract) 361 (PDF)
Jian-Lan Wang, Wen Gu, Shi-Fa Wang

Abstract


New N-alkylfurfurylacetamides were synthesized and characterized from abundant biomass derived furfural by a simple and straightforward procedure with overall yields of 51 to 92%. The antimicrobial activity of the synthesized compounds were then investigated and it was found that N-benzyl-N-furfurylacetamide and N-cyclohexyl-N-furfurylacetamide showed promising activity against bacteria, particularly white-rot-fungi, suggesting a feasible new type of anti-fungal agent in applications to protection and conservation of cultural heritage.

Keywords


Furfural; N-alkyl furfurylamines; N-alkyl-N-furfurylacetamide; Antibiotic activity; White-rot-fungi

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DOI: https://doi.org/10.26789/AEB.2019.01.002
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Copyright (c) 2019 Jian-Lan Wang, Wen Gu, Shi-Fa Wang

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