Applied Environmental Biotechnology

ISSN2382-6436(print) | ISSN: 2424-9092(online)

Editor-in-Chief:Yunjiang Yu

Article Processing Charges:1600(USD)

Publishing Frequency: semi-yearly

Publishing Model : Open Access


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Applied Environmental Biotechnology(AEB) is an open access journal published by Urban Development Scientific Publishing. The purpose of this journal is to understand the latest advances, innovation and technologies of applied environmental biotechnology, and by doing so, to promote active communication and collaborations among the environmental biotechnology scientists around the world. Authors and readers should be included in the following areas: biotechnology, environmental, microbial, metabolism, degradation, bioproducts, ecosystem, water research and other related fields.  All articles submitted to AEB will undergo a rigorous double-blind peer review, and all published articles can be downloaded and read for free. AEB will pay wide attention to the trends in related fields and insist on publishing original research work of highest quality. 

AEB has been indexed in Scopus, CNKI, Google Scholar, etc.


Announcements

 

CiteScore(Scopus) & Mock Impact Factor(Web of Science)

 

The CiteScore(2020) of Applied Environmental Biotechnology is 2.

The mock Impact Factor of Applied Environmental Biotechnology is about 1.5;

 
Posted: 2021-03-17
 
More Announcements...


Vol 7, No 1 (2022)

Table of Contents

Research Articles

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Mohammad A. Alkafaween, Mohammad Abu-Sini, Hamid A. Nagi Al-Jamal
DOI:10.26789/AEB.2022.01.002

Abstract

Staphylococcus aureus is one of the most common pathogens in biofilm-associated chronic infections. S. aureus that live within biofilms avoid the host's immune response and are more resistant to antibiotics than planktonic bacteria. The current study was conducted to evaluate the antibacterial, antibiofilm and antivirulence of seven antibiotics (Ciprofloxacin (CP), Gentamicin (GEN), Tetracycline (TET), Amikacin (AMK), Clindamycin (CLI), Erythromycin (Ery) and Vancomycin (VAN) against S. aureus. The effects of seven antibiotics (CP, AMK, VAN, TET GEN, Ery and CLI) on S. aureus planktonic and biofilm were determined via Antibiotic susceptibility test, Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), disruption of microcolony, biofilm inhibition and degradation (crystal violet staining) and RT-qPCR. Antibiotic susceptibility test showed that CP, AMK, VAN, TET GEN, Ery and CLI has antibacterial activity against S. aureus with an inhibition zone of 28 mm, 21 mm, 27 mm, 20 mm, 25 mm, 27 mm and 19 mm respectively. The results showed that CP and AMK possessed the lowest MIC value against S. aureus with 0.125 µg/mL and 0.25 µg/mL for VAN, TET and GEN and 1.0 for Ery and CLI. The recorded values for MBCs were 0.25 μg for CP and AMK for S. aureus, 0.5 μg for vancomycin, tetracycline and gentamicin for S. aureus and 1.0 μg for Ery and CLI for S. aureus. Notably, CP and AMK demonstrated considerable efficacy, as shown by the low values for MIC; 0.125 μg and MBC; 0.25 μg for S. aureus. All antibiotics were found to disrupt microcolony formation in S. aureus at MIC of each antibiotics. At 0.25 μg concentration to 8 μg concentration of each antibiotic were significantly found to degrade and inhibit biofilm formation of S. aureus. The RT-qPCR showed that four genes including argF, purC, adh, and fabG were downregulated, whilst, three genes including scdA, pykA and menB were upregulated after exposure to CP, AMK, VAN, TET GEN, Ery and CLI. This study showed the efficacy of seven antibiotics against planktonic, biofilm, gene expression and that different concentrations of antibiotics have different degrees of potential effect on established biofilm. In addition, a decreased expression of virulence genes in S. aureus will impact their pathogenicity. These results provide the theoretical parameters for the selection of effective antimicrobial in clinical therapy and demonstrate how to correctly use antibiotics at MIC and sub-MIC as preventive drugs.

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Opinion

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Ji-Dong Gu
DOI:10.26789/AEB.2022.01.001

Abstract

Science is experiencing a different model for a wider dissemination with the widely accessibility of internet today at the information age and high connectivity. This technological development has changed the daily life of peoples globally and has been mainly appraised with positive effects, but very little, if any, negative ones are being discussed, specifically on fundamental matters. In this article I would like to present the emerging negativities and potential detrimental effects on science and its advances to be made. Popularization and population are two words chosen and used here to describe the way in which dissemination of available and accessible scientific information is being made. The new Open Access model of publication and its apparent dominance in the academic publishing market by commercial companies for publication of scientific papers are passing the threshold point and eroding the quality of science in my view. Scientific societies as the most important groups to the establishment of academic standards and to keep new science discoveries to be checked are increasingly forced to cope with the commercial publication practices in terms of speeding up the reviewing and publishing more and quickly, competing for the publishing market and profit to be made, and most importantly, compromising the academic standards. When profit is the major driving force for the publishers, including scientific societies, quality of science in academic papers is yielded to the financial interest and profit, and the purposes of publishing are not for science and its development as the goal. The role of scientific publication in our society must be checked by relevant administration of the governments and national academies together with the scientific societies so that the quality of academic publication of scientific results in science can be maintained at high confident level to serve the society in a positive manner into the future. Commercial publication is another avenue to allow more scientific results to be published in additional to journals by societies, but the relationship between them must be a quality-based judgement and decision, not a pure business competition for success to rule this market.

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