The endocrine-disrupting plasticizers will stay with us for a long time

Ji-Dong Gu

doi:10.26789/AEB.2018.01.008

The endocrine-disrupting plasticizers will stay with us for a long time

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Ji-Dong Gu

Abstract

Many synthetic chemicals are widely used in our daily products and they are in constant contacts with humans through many different routes of exposure. In addition to the toxic environmental pollutants known with diminishing usage, plasticizers, a new class of emerging chemicals, are becoming of human health concerns increasingly. Microbial degradation of plasticizers is generally known, but the toxicity and other effects on human and animals are less well understood, especially in terms of reproductive development and endocrine-disrupting activity. Their major impact to Earth is the large quantities of them used on a daily basis and close contacts with biota of the biosphere. Knowledge of their impact shall be focused more specifically on developmental and endocrine system of animals than mortality in traditional toxicology as an end-point to better assess the threats to the biosphere. New directions on this research topic are presented to advance new knowledge in the future research and development.

Keywords

Biodegradation; Plasticizer; Endocrine disruption; Reproductive development; Mineralization

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References

Chen, C.H., Jiang, S.S., Chang, I.S., Wen, H.J., Sun, C.W. and Wang, S.L., 2018. Association between fetal exposure to phthalate endocrine disruptor and genome-wide DNA methylation at birth. Environmental Research, 162, 261-270.

https://doi.org/10.1016/j.envres.2018.01.009

Cheung, J.K.H., Lam, R.K.W., Shi, M.Y. and Gu, J.D., 2007. Environmental fate of endocrine-disrupting dimethyl phthalate esters (DMPE) under sulfate-reducing condition. Science of the total environment, 381(1-3), 126-133.

https://doi.org/10.1016/j.scitotenv.2007.03.030

Corsini, E., Ruffo, F. and Racchi, M., 2018. Steroid Hormones, Endocrine Disrupting Compounds and Immunotoxicology. Current Opinion in Toxicology, 10, 69-73.

https://doi.org/10.1016/j.cotox.2018.01.006

Fan, Y., Wang, Y., Qian, P.Y. and Gu, J.D., 2004. Optimization of phthalic acid batch biodegradation and the use of modified Richards model for modelling degradation. International Biodeterioration & Biodegradation, 53(1), 57-63.

https://doi.org/10.1016/j.ibiod.2003.10.001

Gu, J.-D., 2003. Microbiological deterioration and degradation of synthetic polymeric materials: recent research advances. International Biodeterioration & Biodegradation, 52(2), 69-91.

https://doi.org/10.1016/S0964-8305(02)00177-4

Gu, J.-D., 2007. Microbial colonization of polymeric materials for space applications and mechanisms of biodeterioration: a review. International Biodeterioration & Biodegradation, 59(3), 170-179.

https://doi.org/10.1016/j.ibiod.2006.08.010

Gu, J.-D., 2016a. Biodegradation testing: so many tests but very little new innovation. Applied Environmental Biotechnology, 1(1), 92-95.

http://dx.doi.org/10.18063/AEB.2016.01.007

Gu, J.-D., 2016b. More than simply bacterial growth curves. Applied Environmental Biotechnology 1(2),,6365.

http://dx.doi.org/10.18063/AEB.2016.02.007

Gu, J.-D., 2017. Biodegradability of plastics: the pitfalls. Applied Environmental Biotechnology, 2(1), 59-61.

http://dx.doi.org/10.26789/AEB.2017.01.008

Gu, J.-D., and Wang, Y. (2013) Microbial transformation of phthalate esters: diversity of hydrolytic esterases. pp. 313345. In: Wong MH (ed), Environmental Contamination: Health Risks and Ecological Restoration. CRC Press, Boca Raton, Florida.

Gu, J.-D., Ford, T., Thorp, K. and Mitchell, R., 1996. Microbial growth on fiber reinforced composite materials. International Biodeterioration & Biodegradation, 37(3-4), 197-204.

https://doi.org/10.1016/S0964-8305(96)00035-2

Gu, J.-D., Ford, T., Thorp, K. and Mitchell, R., 2011. Chapter 30: Microbial degradation of polymeric materials. Pages 421438. In: W Revie, (ed.), The Uhlig Corrosion Handbook (3rd ed), John Wiley & Sons, New York.

Kleerebezem, R., Pol, L.W.H. and Lettinga, G., 1999. Anaerobic biodegradability of phthalic acid isomers and related compounds. Biodegradation, 10(1), 63-73.

https://doi.org/10.1023/A:1008321015498

Kurane, R., 1997. Microbial degradation and treatment of polycyclic aromatic hydrocarbons and plasticizers. Annals of the New York Academy of Sciences, 829(1), 118-134.

https://doi.org/10.1111/j.1749-6632.1997.tb48570.x

Li, J. and Gu, J.D., 2006a. Biodegradation of dimethyl terephthalate by Pasteurella multocida Sa follows an alternative biochemical pathway. Ecotoxicology, 15(4), 391-397.

https://doi.org/10.1007/s10646-006-0070-8

Li, J. and Gu, J.D., 2006b. Biochemical cooperation between Klebsiella oxytoca Sc and Methylobacterium mesophilium Sr for complete degradation of dimethyl isophthalate. Water, Air, & Soil Pollution: Focus, 6(5-6), 569-574.

https://doi.org/10.1007/s11267-006-9041-6

Li, J. and Gu, J.D., 2007. Complete degradation of dimethyl isophthalate requires the biochemical cooperation between Klebsiella oxytoca Sc and Methylobacterium mesophilicum Sr isolated from wetland sediment. Science of the Total Environment, 380(1-3), 181-187.

https://doi.org/10.1016/j.scitotenv.2006.12.033

Li, J., Gu, J.D. and Pan, L., 2005a. Transformation of dimethyl phthalate, dimethyl isophthalate and dimethyl terephthalate by Rhodococcus rubber Sa and modeling the processes using the modified Gompertz model. International Biodeterioration & Biodegradation, 55(3), 223-232.

https://doi.org/10.1016/j.ibiod.2004.12.003

Li, J., Gu, J.D. and Yao, J.H., 2005b. Degradation of dimethyl terephthalate by Pasteurella multocida Sa and Sphingomonas paucimobilis Sy isolated from mangrove sediment. International Biodeterioration & Biodegradation, 56(3), 158-165.

https://doi.org/10.1016/j.ibiod.2005.07.001

Luo, Z.H., Pang, K.L., Wu, Y.R., Gu, J.D., Chow, R.K. and Vrijmoed, L.L.P., 2012. Degradation of phthalate esters by Fusarium sp. DMT-5-3 and Trichosporon sp. DMI-5-1 isolated from mangrove sediments. Pages . In: Raghukumar C (ed), Biology of Marine Fungi. Springer-Verlag, Heidelberg, Germany.

https://doi.org/10.1007/978-3-642-23342-5_15

Schwarzenbach, R.P., Escher, B.I., Fenner, K., Hofstetter, T.B., Johnson, C.A., Von Gunten, U. and Wehrli, B., 2006. The challenge of micropollutants in aquatic systems. Science, 313(5790), 1072-1077.

https://doi.org/10.1126/science.1127291

Wang, Y. and Gu, J.D., 2006a. Degradation of dimethyl terephthalate by Variovorax paradoxus T4 and Sphingomonas paucimobilis DOS1 of the South China Sea. Ecotoxicology, 15, 549-557.

https://doi.org/10.1007/s10646-006-0093-1

Wang, Y.P. and Gu, J.D., 2006. Degradation of dimethyl isophthalate by Viarovorax paradoxus strain T4 isolated from deep-ocean sediment of the South China Sea. Human and Ecological Risk Assessment, 12(2), 236-247.

https://doi.org/10.1080/10807030500531521

Wang, Y., Fan, Y. and Gu, J.D., 2004. Dimethyl phthalate ester degradation by two planktonic and immobilized bacterial consortia. International Biodeterioration & Biodegradation, 53(2), 93-101.

https://doi.org/10.1016/j.ibiod.2003.10.005

Wang, Y., Yin, B., Hong, Y., Yan, Y. and Gu, J.D., 2008. Degradation of dimethyl carboxylic phthalate ester by Burkholderia cepacia DA2 isolated from marine sediment of South China Sea. Ecotoxicology, 17(8), 845-852.

https://doi.org/10.1007/s10646-008-0247-4

Wenzel, A.G., Brock, J.W., Cruze, L., Newman, R.B., Unal, E.R., Wolf, B.J., Somerville, S.E. and Kucklick, J.R., 2018. Prevalence and predictors of phthalate exposure in pregnant women in Charleston, SC. Chemosphere, 193, 394-402.

https://doi.org/10.1016/j.chemosphere.2017.11.019

Wong, K.H. and Durrani, T.S., 2017. Exposures to Endocrine Disrupting Chemicals in Consumer Products—A Guide for Pediatricians. Current Problems in Pediatric and Adolescent Health Care, 47(5), 107-118.

Xu, X.R., Li, H.B. and Gu, J.D., 2005. Biodegradation of an endocrine-disrupting chemical di-n-butyl phthalate ester by Pseudomonas fluorescens B-1. International Biodeterioration & Biodegradation, 55(1), 9-15.

https://doi.org/10.1016/j.ibiod.2004.05.005

Xu, X.R., Li, H.B. and Gu, J.D., 2006. Elucidation of n-butyl benzyl phthalate biodegradation using high-performance liquid chromatography and gas chromatography–mass spectrometry. Analytical and Bioanalytical Chemistry, 386(2), 370-375.

https://doi.org/10.1007/s00216-006-0627-7

Yip, K.C.W. and Gu, J.D., 2016. A novel bacterium involved in the degradation of 2-methylindole isolated from sediment of Inner Deep Bay of Hong Kong. Applied Environmental Biotechnology, 1(1), 52-63.

http://dx.doi.org/10.18063/AEB.2016.01.008

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DOI: https://doi.org/10.26789/AEB.2018.01.008

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