Antibacterial and antioxidant activity of green synthesized Zinc oxide nanoparticles using polyphenol extract from Mentha piperita seeds

AbdulAziz Mohamed Gad

Antibacterial and antioxidant activity of green synthesized Zinc oxide nanoparticles using polyphenol extract from Mentha piperita seeds

VIEWS - 137 (Abstract)

AbdulAziz Mohamed Gad

Abstract

Currently green nanotechnology presents a smart solution to produce novel nanostructured materials that are highly safe and environmentally friendly. In this work, zinc oxide nanoparticles (ZnO NPs) were prepared by employing aqueous mint (M. piperita) seeds extract at 60 ^oC, as a green synthesis method. Mint seeds extract was chosen among the 6 plant seeds that were the subject of this study as it represents the highest polyphenol and flavonoid seeds extract as well as antioxidant activity. High Performance Liquid Chromatography (HPLC) showed that syringic acid (16%), rutin (22%), and apigenin-7-O-glucoside (29%) were the main component of 70% ethanol mint seeds extract. The obtained ZnO NPs were examined using an ultraviolet-visible spectrophotometer (UV-VIS), X-ray diffraction (XRD) and transmission electron microscope (TEM). The UV spectrum revealed maximum absorption value at 376 nm, related to bio-syntheized ZnO NPs. The XRD study demonstrated the creation of ZnO NPs. The green synthesized ZnO NPs were spherical in shape with average particles size 80±36 nm. Antibacterial activity of aqueous mint seeds extract and synthesized ZnO NPs were investigated on E. coli and S. aureus and antioxidant activity as well.

Keywords

flavonoids, HPLC, Mint, aqueous extract, syringic acid, rutin

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